As such, molecules involved in signal transduction are enriched within cilia and regulating their ciliary concentrations allows adaptation to the
Explore the ultimate guide to optical modules. Learn types, functions, performance metrics & how to choose the right module for your fiber network.
Here, we present polycaprolactone (PCL)/graphene cilia sensing arrays that combine the control and ease of fabrication of 3D printing with contact-resistance
The rod and cone photoreceptor cells of the vertebrate retina have highly specialized structures that enable them to carry out their function of light detection over a broad range of
The significance of primary cilia in normal physiology and disease pathology is increasingly being recognized as our understanding of the unique
This review provides an overview of the current state of research on artificial cilia, and mainly introduces their actuation types, fabrication methods and practical applications.
Here, we review emerging evidence that in addition to their well-established roles in sight, smell, and mechanosensation, primary cilia are key
Ciliary dysfunction causes a large group of developmental and degenerative human diseases known as ciliopathies. These diseases reflect the critical roles that cilia
This chapter reviews the current understanding of the various mechanisms involved in cilia and flagellar assembly and maintenance. Consistent with the nearly ubiquitous cellular distribution, cilia have
Results: Optical imaging has become a crucial tool for studying ciliary structure and function, providing high-resolution, non-invasive imaging
We present an endoscopic configuration for measuring the motion frequency of cilia in the nasal cavity. The technique is based on temporal
Super-resolution (SR) microscopy has been used to observe structural details beyond the diffraction limit of ∼250 nm in a variety of biological and materials
Primary cilia project from the surface of most vertebrate cells and are key in sensing extracellular signals and locally transducing this information into a cellular response. Recent findings
The mechanisms underlying compartmentalization of cilia are an area of intense current research. Recent findings have revealed similarities and
Cilia in most eukaryotic cells are tiny, hair-like organelles built around a central core of microtubules, surrounded by a thin layer of cytoplasm and a ciliary membrane of unique composition.
Mutations that affect primary cilia cause ciliopathies with variable severity and expressivity. The diversity of cilia across cell types, tissues and developmental stages enables their
In this Review, we highlight recent advances in imaging modalities that have significantly deepened our understanding of centriolar and ciliary structure and function.
Hair cells in the human ear contain cilia of varying lengths that sense varied acoustic signals. Here, inspired by this, we report an artificial cilia-based
In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of
Thus, the prevalence of primary cilia in oligodendrocytes in the visual pathway and the age-related changes in ciliation suggest that they may play important roles in the white matter and age
Thus, neuronal cilia may represent a specialized signaling platform that facilitates interactions between receptors and/or signaling cascades to provide an exclusive ciliary signal. Studies are needed to
Examples of an isolated rod photoreceptor cilia from mouse retina tissue samples are compared at the same scale from images captured by transmission electron microscopy (TEM), and by the
Discover the unseen world of tiny, vital cellular structures. Learn how these microscopic elements are explored and their profound impact on biological systems.
Many of these proteins also have functions in the primary cilia of other cell types, so mutations are often associated with other complex multi
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